SLC35D1 Antikörper (N-Term)

Produktnummer ABIN500742

Produktdetails anti-SLC35D1 Antikörper

Target: SLC35D1 (Solute Carrier Family 35 (UDP-Glucuronic Acid/UDP-N-Acetylgalactosamine Dual Transporter), Member D1 (SLC35D1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC35D1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects SLC35D1 / UGTREL7 at N-term. It is predicted to not cross-react with the highly homologous Slc35D2.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Peptide affinity chromatography

Immunogen: Slc35D1 antibody was raised against a 14 amino acid peptide near the amino terminus of the human Slc35D1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu SLC35D1

Target: SLC35D1 (Solute Carrier Family 35 (UDP-Glucuronic Acid/UDP-N-Acetylgalactosamine Dual Transporter), Member D1 (SLC35D1))

Andere Bezeichnung: SLC35D1 / UGTREL7 (SLC35D1 Produkte)

Synonyme: UGTREL7 antikoerper, AI834976 antikoerper, C330011J09 antikoerper, mKIAA0260 antikoerper, UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter antikoerper, solute carrier family 35 member D1 antikoerper, solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1 antikoerper, Tc00.1047053510611.20 antikoerper, Tc00.1047053506793.40 antikoerper, SLC35D1 antikoerper, Slc35d1 antikoerper

Hintergrund: The solute carrier family Slc35 consists of at least 17 proteins that act as nucleotide sugar transporters localized to the Golgi apparatus and endoplasmic reticulum. The role of the ER-resident Slc family member Slc35D1 is to transport both UDP-glucuronic acid and UDP-N-acetylgalactosamine. These molecules can serve as substrates for chondroitin sulfate biosynthesis and mice lacking the Slc35D1 gene developed a lethal form of skeletal dysplasia with severe shortening of limbs and facial structures. Examination of epiphyseal cartilage in these mice revealed a decreased proliferating zone with round chrondrocytes, scarce matrices, and reduced proteoglycan aggregates. Loss of function mutations in human Slc35D1 cause Schneckenbecken dysplasia, a severe skeletal dysplasia.Synonyms: KIAA0260, Solute carrier family 35 member D1, UDP-galactose transporter-related protein 7, UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter, UGTrel7

Gen-ID: 23169

NCBI Accession: NP_055954

UniProt: Q9NTN3

Pathways: Glycosaminoglycan Metabolic Process