INPPL1 Antikörper (pTyr986, pTyr987) (Alexa Fluor 750)

Produktnummer ABIN5005425

Produktdetails anti-INPPL1 Antikörper (Alexa Fluor 750)

Target: INPPL1 (Inositol Polyphosphate Phosphatase-Like 1 (INPPL1))

Bindungsspezifität: pTyr986, pTyr987

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser INPPL1 Antikörper ist konjugiert mit Alexa Fluor 750

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human SHIP2 around the phosphorylation site of Tyr986/987

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu INPPL1

Target: INPPL1 (Inositol Polyphosphate Phosphatase-Like 1 (INPPL1))

Andere Bezeichnung: INPPL1 + (INPPL1 Produkte)

Synonyme: OPSMD antikoerper, SHIP2 antikoerper, 51C antikoerper, Ship2 antikoerper, inppl1 antikoerper, si:bz46j2.7 antikoerper, si:rp71-46j2.7 antikoerper, INPPL1 antikoerper, fc58a04 antikoerper, wu:fc58a04 antikoerper, zgc:198309 antikoerper, inositol polyphosphate phosphatase like 1 antikoerper, inositol polyphosphate phosphatase-like 1 antikoerper, inositol polyphosphate phosphatase-like 1b antikoerper, phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2B antikoerper, inositol polyphosphate phosphatase-like 1a antikoerper, INPPL1 antikoerper, Inppl1 antikoerper, inppl1b antikoerper, LOC100180571 antikoerper, inppl1a antikoerper

Hintergrund:

Synonyms: 4, 5-trisphosphate 5-phosphatase 2, 51C protein, EC 3.1.3.n1, inositol polyphosphate phosphatase like 1, Inositol polyphosphate phosphatase like protein 1, Inositol polyphosphate phosphatase-like protein 1, INPPL-1, INPPL1, Phosphatidylinositol 3, Phosphatidylinositol 3,4,5 trisphosphate 5 phosphatase 2, Protein 51C, SH2 domain containing inositol 5' phosphatase 2, SH2 domain-containing inositol 5''-phosphatase 2, SH2 domain-containing inositol phosphatase 2, SHIP-2, SHIP2, SHIP2_HUMAN.

Background: The steady state of protein tyrosyl phosphorylation in cells is regulated by the opposing action of tyrosine kinases and protein tyrosine phosphatases (PTPs). Several groups have independently identified a non transmembrane PTP, designated SHPTP1 (also known as PTP1C, HCP and SHP), which is primarily expressed in hematopoietic cells and characterized by the presence of two SH2 domains N terminal to the PTP domain. A second and much more widely expressed PTP with SH2 domains, SHPTP2 (also designated PTP1D and Syp), has been identified. SHP2 is a protein tyrosine phosphatase that is widely expressed and plays a regulatory role in various cell signaling events that are important for many cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration.

Gen-ID: 3636

Pathways: Platelet-derived growth Factor Receptor Signaling