PPAPDC2 Antikörper (C-Term)

Produktnummer ABIN500531

Produktdetails anti-PPAPDC2 Antikörper

Target: PPAPDC2 (Phosphatidic Acid Phosphatase Type 2 Domain Containing 2 (PPAPDC2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPAPDC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Peptide affinity chromatography

Immunogen: PPAPDC2 antibody was raised against a 13 amino acid peptide from near the carboxy terminus human PPAPDC2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Referenzen für anti-PPAPDC2 Antikörper (ABIN500531)

Pant, Kocarek: "Role of Phosphatidic Acid Phosphatase Domain Containing 2 in Squalestatin 1-Mediated Activation of the Constitutive Androstane Receptor in Primary Cultured Rat Hepatocytes." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 44, Issue 3, pp. 352-5, (2016) (PubMed).

Details zu PPAPDC2

Target: PPAPDC2 (Phosphatidic Acid Phosphatase Type 2 Domain Containing 2 (PPAPDC2))

Andere Bezeichnung: PPAPDC2 (PPAPDC2 Produkte)

Synonyme: PPAPDC2 antikoerper, PDP1 antikoerper, PSDP antikoerper, bA6J24.6 antikoerper, 4932443D16Rik antikoerper, phospholipid phosphatase 6 antikoerper, PLPP6 antikoerper, plpp6 antikoerper, Plpp6 antikoerper

Hintergrund: PPAPDC2 is a phosphatase that dephosphorylates Presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may have important role in innate immunity. PSDP is a bioactive lipid that rapidly remodels to PSMP upon cell activation. PPAPDC2 displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid. PPAPDC2 activity is independent of Mg2+ and has been identified in activated human neutrophil (PMN) extracts. It is widely expressed in human tissues. Recent studies shows PPAPDC2 is a functional isoprenoid diphosphate phosphatase.Synonyms: PPAP2 domain-containing protein 2, Phosphatidic acid phosphatase type 2 domain-containing protein 2, Presqualene diphosphate phosphatase

Gen-ID: 403313

NCBI Accession: NP_982278

UniProt: Q8IY26