PPAPDC1B Antikörper (N-Term)

Produktnummer ABIN500529

Produktdetails anti-PPAPDC1B Antikörper

Target: PPAPDC1B (Phosphatidic Acid Phosphatase Type 2 Domain Containing 1B (PPAPDC1B))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPAPDC1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects PPAPDC1B.

Aufreinigung: Peptide affinity chromatography

Immunogen: PPAPDC1B antibody was raised against a 14 amino acid peptide near the amino terminus of human PPAPDC1B.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PPAPDC1B

Target: PPAPDC1B (Phosphatidic Acid Phosphatase Type 2 Domain Containing 1B (PPAPDC1B))

Andere Bezeichnung: PPAPDC1B (PPAPDC1B Produkte)

Synonyme: PPAPDC1B antikoerper, DPPL1 antikoerper, HTPAP antikoerper, 1810019D05Rik antikoerper, 2310022A04Rik antikoerper, AW045471 antikoerper, Ppapdc1 antikoerper, phospholipid phosphatase 5 antikoerper, PLPP5 antikoerper, plpp5 antikoerper, Plpp5 antikoerper

Hintergrund: Phosphatidate phosphatase (PAP) plays important role in lipid-signaling metabolism in eukaryotic cells. Two distinct types of PAP (PAP1 and PAP2) activity have been distinguished by their subcellular localization and differential sensitivity to N-ethylmaleimide (NEM) and Mg2+. A yeast diacylglycerol pyrophosphate (DGPP) phosphatase (DPP1) and mammalian DGPP phosphatase (PAP2) have been identified as Mg2+-independent and NEM-insensitive membrane-associated. PPAPDC1A (also known as DPPL2) and PPAPDC1B (DPPL1) form a novel type of Mg2+-independent and NEM-sensitive mammalian phosphatidate phosphatase showing broad substrate specificity. Knockdown experiments indicated that this protein is involved with multiple cell signaling pathways, including the JAK-Stat3, MAP kinase, and PKC pathways. PPAPDC1B may also potentiate the estrogen receptor pathway by down-regulating DUSP22.Synonyms: DPPL1, HTPAP, Phosphatidate phosphatase PPAPDC1B, Phosphatidic acid phosphatase type 2 domain-containing protein 1B

Gen-ID: 84513

NCBI Accession: NP_001096029

UniProt: Q8NEB5