PLEKHM3 Antikörper (C-Term)

Produktnummer ABIN500513

Produktdetails anti-PLEKHM3 Antikörper

Target: PLEKHM3 (Pleckstrin Homology Domain Containing, Family M, Member 3 (PLEKHM3))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLEKHM3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Peptide affinity chromatography

Immunogen: PLEKHM3 antibody was raised against a 13 amino acid peptide from near the carboxy terminus of human PLEKHM3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu PLEKHM3

Target: PLEKHM3 (Pleckstrin Homology Domain Containing, Family M, Member 3 (PLEKHM3))

Andere Bezeichnung: PLEKHM3 (PLEKHM3 Produkte)

Synonyme: PLEKHM1L antikoerper, DAPR antikoerper, 9430067K14Rik antikoerper, A230102O09Rik antikoerper, AI449570 antikoerper, Plekhm1l antikoerper, Dapr antikoerper, RGD1307151 antikoerper, pleckstrin homology domain containing, family M, member 3 antikoerper, pleckstrin homology domain containing M3 antikoerper, pleckstrin homology domain containing M3 L homeolog antikoerper, PLEKHM3 antikoerper, Plekhm3 antikoerper, plekhm3.L antikoerper

Hintergrund: PLEKHM3, also known as DAPR, is a member of the M family of Pleckstrin homology domain-containing proteins. PLEKHM3 was initially identified through chromatin immunoprecipitation and CpG microarray analysis examining proteins regulated by myocyte-enhancing factor 2. In C2C12 myoblast cells, PLEKHM3 binds to the PI3K signaling member protein kinase B in the cytosol prior to differentiation into myotubes. Following the initiation of differentiation, PLEKHM3 was also found in membrane fractions. Knockdown of PLEKHM3 expression by RNAi resulted in the inhibition of myotube formation, suggesting that PLEKHM3 is a key component required by myoblasts for orchestrating their differentiation during myogenesis.Synonyms: PH domain-containing family M member 3, PLEKHM1L, Pleckstrin homology domain-containing family M member 3

Gen-ID: 389072

UniProt: Q6ZWE6