PLEKHM2
Reaktivität: Human
ELISA, WB, IHC, IF
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
1.0 mg/mL
Buffer
PBS containing 0.02 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
-20 °C
Informationen zur Lagerung
Store the antibody (in aliquots) at -20 °C.
Target
PLEKHM2
(Pleckstrin Homology Domain Containing, Family M (With RUN Domain) Member 2 (PLEKHM2))
zgc:194971 antikoerper, RP11-169K16.1 antikoerper, SKIP antikoerper, 2310034J19Rik antikoerper, AI854247 antikoerper, mKIAA0842 antikoerper, pleckstrin homology and RUN domain containing M2 antikoerper, pleckstrin homology domain containing, family M (with RUN domain) member 2 antikoerper, PLEKHM2 antikoerper, plekhm2 antikoerper, Plekhm2 antikoerper
Hintergrund
PLEKHM2, also known as SKIP, is a member of the M family of Pleckstrin homology domain-containing proteins. While little is known of PLEKHM2, a recent study examining differential gene expression in human hematopoietic stem cells has shown it to be specifically expressed in stem cells, suggesting that PLEKHM2 may play a role in erythroid commitment and development. Other studies have shown that PLEKHM2 is required for interaction with the Salmonella virulence factor SifA for Salmonella pathogenesis, suggesting that PLEKHM2 has cellular roles other than in the developing embryo.Synonyms: KIAA0842, PH domain-containing family M member 2, Pleckstrin homology domain-containing family M member 2, SKIP, Salmonella-induced filaments A and kinesin-interacting protein, SifA and kinesin-interacting protein