SLC9A1 Antikörper (Center)

Produktnummer ABIN500341

Produktdetails anti-SLC9A1 Antikörper

Target: SLC9A1 (Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 (SLC9A1))

Bindungsspezifität: Center

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC9A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects SLC9A1 / NHE1 at center.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Peptide affinity chromatography

Immunogen: Nhe-1 antibody was raised against a 17 amino acid peptide near the center of the human Nhe-1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu SLC9A1

Target: SLC9A1 (Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 (SLC9A1))

Andere Bezeichnung: SLC9A1 / NHE1 (SLC9A1 Produkte)

Synonyme: AT-NHX1 antikoerper, ATNHX antikoerper, ATNHX1 antikoerper, NA(+)/H(+) ANTIPORTER antikoerper, Na+/H+ exchanger 1 antikoerper, T21B4.60 antikoerper, T21B4_60 antikoerper, AW554487 antikoerper, Apnh antikoerper, Nhe1 antikoerper, swe antikoerper, NHE-1 antikoerper, NHE1 antikoerper, APNH antikoerper, Na+/H+ exchanger 1 antikoerper, solute carrier family 9 (sodium/hydrogen exchanger), member 1 antikoerper, solute carrier family 9 member A1 antikoerper, NHX1 antikoerper, Slc9a1 antikoerper, SLC9A1 antikoerper

Hintergrund: The Na+/H+ antiporter (Nhe-1) is a ubiquitous membrane-bound enzyme involved in pH regulation of vertebrate cells and is specifically inhibited by the diuretic drug amiloride and activated by a variety of signals including growth factors, mitogens, neurotransmitters, and tumor promoters. Nhe-1 acts as an anchor for actin filaments to control the integrity of the cortical cytoskeleton. This occurs through a previously unrecognized structural link between Nhe-1 and the actin-binding proteins ezrin, radixin, and moesin, collectively referred to as ERM proteins. A structural role for Nhe-1 has been proposed in regulating the cortical cytoskeleton that is independent of its function as an ion exchanger. It is also thought that Nhe-1 play a role in hypertension. At least two isoforms of Nhe-1 are known to exist.Synonyms: APNH, APNH1, Na(+)/H(+) antiporter, Na(+)/H(+) exchanger 1, Sodium/hydrogen exchanger 1, Solute carrier family 9 member 1, amiloride-sensitive

Gen-ID: 6548

UniProt: P19634

Pathways: Glycosaminoglycan Metabolic Process, Proton Transport