LRFN2 Antikörper (C-Term)

Produktnummer ABIN500188

Produktdetails anti-LRFN2 Antikörper

Target: LRFN2 (Leucine Rich Repeat and Fibronectin Type III Domain Containing 2 (LRFN2))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRFN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects LRFN2. It is predicted to not cross-react with other members of the LRFN family.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Peptide affinity chromatography

Immunogen: LRFN2 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human LRFN2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu LRFN2

Target: LRFN2 (Leucine Rich Repeat and Fibronectin Type III Domain Containing 2 (LRFN2))

Andere Bezeichnung: LRFN2 (LRFN2 Produkte)

Synonyme: FIGLER2 antikoerper, KIAA1246 antikoerper, RP11-535K1.2 antikoerper, SALM1 antikoerper, 5730420O05Rik antikoerper, mKIAA1246 antikoerper, Salm1 antikoerper, leucine rich repeat and fibronectin type III domain containing 2 antikoerper, LRFN2 antikoerper, Lrfn2 antikoerper

Hintergrund: LRFN2 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system. At least two isoforms of LRFN2 are known to exist.Synonyms: KIAA1246, Leucine-rich repeat and fibronectin type-III domain-containing protein 2, SALM1

Gen-ID: 57497

UniProt: Q9ULH4

Pathways: Synaptic Membrane