CRH Antikörper (AA 185-196) (Alexa Fluor 750)

Produktnummer ABIN5000516

Produktdetails anti-CRH Antikörper (Alexa Fluor 750)

Target: CRH (Corticotropin Releasing Hormone (CRH))

Bindungsspezifität: AA 185-196

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRH Antikörper ist konjugiert mit Alexa Fluor 750

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Pig,Chicken,Rabbit,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CRF

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CRH

Target: CRH (Corticotropin Releasing Hormone (CRH))

Andere Bezeichnung: CRF (CRH Produkte)

Synonyme: CRF antikoerper, Gm1347 antikoerper, crf antikoerper, crh antikoerper, zgc:101864 antikoerper, CRH antikoerper, corticoliberin antikoerper, crhb antikoerper, crh.1-a antikoerper, crha antikoerper, corticotropin releasing hormone antikoerper, corticotropin releasing hormone b antikoerper, corticotropin releasing hormone S homeolog antikoerper, corticotropin releasing hormone L homeolog antikoerper, Crh antikoerper, CRH antikoerper, crhb antikoerper, crh antikoerper, crh.S antikoerper, crh.L antikoerper

Hintergrund:

Synonyms: Corticoliberin, Corticoliberin precursor, Corticotropin releasing factor, Corticotropin releasing hormone, Corticotropin releasing hormone deficiency included, crf, crh, crh deficiency included, corticoliberin preproprotein, CRF_HUMAN, Corticotropin-releasing factor, CRF, CRH, Corticotropin-releasing hormone.

Background: Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition. [provided by RefSeq, Apr 2010].

Gen-ID: 1392

UniProt: P06850

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Activity, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Feeding Behaviour