C1QTNF2 Antikörper (Intermediate Domain)

Produktnummer ABIN499662

Produktdetails anti-C1QTNF2 Antikörper

Target: C1QTNF2 (C1q and Tumor Necrosis Factor Related Protein 2 (C1QTNF2))

Bindungsspezifität: Intermediate Domain

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C1QTNF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: Rabbit CTRP2 polyclonal antibody was raised against a 16 amino acid peptide from near the center of human CTRP2.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Human CTRP2 (Intermediate Domain) Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: CTRP2 polyclonal antibody can be used for the detection of CTRP2 at 2 - 4 μg/mL. These proteins are often highly modified post-translationally and migrate inSDS-PAGE at positions other than their predicted size. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu C1QTNF2

Target: C1QTNF2 (C1q and Tumor Necrosis Factor Related Protein 2 (C1QTNF2))

Andere Bezeichnung: C1QTNF2 (C1QTNF2 Produkte)

Synonyme: C1QTNF2 antikoerper, fe50b04 antikoerper, wu:fe50b04 antikoerper, CTRP2 antikoerper, zacrp2 antikoerper, 1810033K05Rik antikoerper, Ctrp2 antikoerper, RGD1561041 antikoerper, C1q and tumor necrosis factor related protein 2 antikoerper, C1q and TNF related 2 antikoerper, C1QTNF2 antikoerper, c1qtnf2 antikoerper, C1qtnf2 antikoerper

Hintergrund: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-related proteins (CTRPs) 1-7 (2). Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues (3). These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene (4). Of the CTRPs, CTRP2 is most similar structurally and functionally to adiponectin. Recombinant CTRP2 rapidly activated AMPK and MAPK in cultured C2C12 cells, leading to increased glycogen accumulation and fatty acid oxidation (3).Synonyms: CTRP2, Complement C1q tumor necrosis factor-related protein 2

Gen-ID: 114898

NCBI Accession: NP_114114

UniProt: Q9BXJ5