C1QTNF1 Antikörper (N-Term)

Produktnummer ABIN499660

Produktdetails anti-C1QTNF1 Antikörper

Target: C1QTNF1 (C1q and Tumor Necrosis Factor Related Protein 1 (C1QTNF1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C1QTNF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: CTRP1 (NT) antibody was raised against a 15 amino acid peptide from near the amino-terminus of human CTRP1.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Human CTRP1 / G protein coupled receptor interacting protein 1 / GIP (N-Terminus) Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: CTRP1 antibody can be used for the detection of CTRP1 at 1 μg/mL. Theseproteins are often highly modified post-translationally and migrate in SDS-PAGE atpositions other than their predicted size. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu C1QTNF1

Target: C1QTNF1 (C1q and Tumor Necrosis Factor Related Protein 1 (C1QTNF1))

Andere Bezeichnung: C1QTNF1 (C1QTNF1 Produkte)

Synonyme: C1QTNF1 antikoerper, CTRP1 antikoerper, GIP antikoerper, ZSIG37 antikoerper, 1600017K21Rik antikoerper, Zsig37 antikoerper, Ctrp1 antikoerper, zgc:113062 antikoerper, C1q and tumor necrosis factor related protein 1 antikoerper, C1q and TNF related 1 antikoerper, C1QTNF1 antikoerper, c1qtnf1 antikoerper, C1qtnf1 antikoerper

Hintergrund: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-related proteins (CTRPs) 1-7 (2). Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues (3). These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene (4). In obese (ob/ob) mice, RT-PCR analysis showed that mCTRP1 transcripts are seen at substantially higher levels in adipose tissues compared to those of normal mice (3).Synonyms: CTRP1, Complement C1q tumor necrosis factor-related protein 1, G protein-coupled receptor-interacting protein, GIP

Gen-ID: 114897

NCBI Accession: NP_940995

UniProt: Q9BXJ1