Aggrecan Antikörper (AA 601-700) (Alexa Fluor 680)
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- Target Alle Aggrecan (ACAN) Antikörper anzeigen
- Aggrecan (ACAN)
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Bindungsspezifität
- AA 601-700
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Reaktivität
- Ratte, Maus, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Aggrecan Antikörper ist konjugiert mit Alexa Fluor 680
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Applikation
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from Human Aggrecan
- Isotyp
- IgG
- Top Product
- Discover our top product ACAN Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- Aggrecan (ACAN)
- Andere Bezeichnung
- Aggrecan (ACAN Produkte)
- Synonyme
- AGC1 antikoerper, AGCAN antikoerper, CSPG1 antikoerper, CSPGCP antikoerper, MSK16 antikoerper, SEDK antikoerper, Agc antikoerper, Agc1 antikoerper, Cspg1 antikoerper, b2b183Clo antikoerper, cmd antikoerper, aggrecan antikoerper, aggrecan core protein antikoerper, ACAN antikoerper, Acan antikoerper, LOC100380783 antikoerper, AGC antikoerper
- Hintergrund
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Synonyms: AGC1, CSPG1, MSK16, Cartilage-specific proteoglycan core protein, CSPCP, Aggrecan core protein, Chondroitin sulfate proteoglycan 1
Background: The large chondroitin sulfate proteoglycan, aggrecan, is the predominant proteoglycan present in cartilage. Aggrecan is a member of the chondroitin sulphate proteoglycan family, which also includes versican/PG-M, neurocan and brevican. Aggrecan is a complex multidomain macromolecule that undergoes extensive processing and post-translational modification. Aggrecan in cartilage forms aggregates with hyaluronan and link protein, embedded in a collagen network. Aggrecan accounts for the compressive stiffness and resilience of the hyaline cartilage. Many forms of inflammatory arthritis are shown to be accompanied with aggrecan degradation and loss from the cartilage. Brevican is a brain proteoglycan of the aggrecan/versican/neurocan family. In the adult brain, the brevican core protein undergoes proteolytic cleavage and exists as a full-length form a carboxy-terminal fragment and an amino-terminal fragment.
- UniProt
- P16112
- Pathways
- Glycosaminoglycan Metabolic Process, Dicarboxylic Acid Transport
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