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NCR1 Antikörper
NCR1
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
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Target
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NCR1
(Natural Cytotoxicity Triggering Receptor 1 (NCR1))
Reaktivität
Alle Reaktivitäten für NCR1 Antikörper
Human
Wirt
Alle Wirte für NCR1 Antikörper
Kaninchen
Klonalität
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Polyklonal
Konjugat
Alle Konjugate für NCR1 Antikörper
Dieser NCR1 Antikörper ist unkonjugiert
Applikation
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Western Blotting (WB)
Spezifität
This antibody detects endogenous levels of CD335 / NKp46. (region surrounding Pro176)
Kreuzreaktivität (Details)
Species reactivity (tested):Human.
Aufreinigung
Affinity chromatography using epitope-specific immunogen
Reinheit
> 95 % (by SDS-PAGE)
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Anwendungsinformationen
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Applikationshinweise
Western blot: 1: 500 - 1: 1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
1.0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.2, 15 mM sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Details zu NCR1
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Target
NCR1
(Natural Cytotoxicity Triggering Receptor 1 (NCR1))
Andere Bezeichnung
CD335 / NKp46 (NCR1 Produkte )
Synonyme
CD335 antikoerper, LY94 antikoerper, NK-p46 antikoerper, NKP46 antikoerper, Ly94 antikoerper, NKp46 antikoerper, KILR-1 antikoerper, Nk-p46 antikoerper, Nkp46 antikoerper, natural cytotoxicity triggering receptor 1 antikoerper, NCR1 antikoerper, Ncr1 antikoerper
Hintergrund
NKp46 (lymphocyte antigen 94, LY94) is a natural cytotoxicity receptor that belongs to the immunoglobulin superfamily and is expressed by all resting or activated NK cells, but not on T cells or B cells. The NKp46 cDNA encodes a 304 amino acid type I transmembrane protein with an extracellular region preceded by a 21 residue signal peptide and two cysteine-bridged C2-type Ig-like domains. A stem connects the extracellular domain to a 19 amino acid, arginine containing-transmembrane domain. NKp46 is involved in natural cytotoxicity and is involved in the recognition and lysis of both human and murine tumor cells.Synonyms: LY94, NCR1, NK cell-activating receptor, NKp46, Natural cytotoxicity triggering receptor, Natural killer cell p46-related protei
Molekulargewicht
approx. 38 kDa
Gen-ID
9437
NCBI Accession
NP_004820
UniProt
O76036
Pathways
Regulation of Leukocyte Mediated Immunity
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