FOLR1 Antikörper
-
- Target Alle FOLR1 Antikörper anzeigen
- FOLR1 (Folate Receptor 1 (Adult) (FOLR1))
-
Reaktivität
- Human, Ratte, Maus
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser FOLR1 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Spezifität
- This antibody detects endogenous levels of FR-α (Y80) protein. (region surrounding Tyr80)
- Kreuzreaktivität (Details)
-
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Aufreinigung
- Affinity chromatography using epitope-specific immunogen
- Reinheit
- > 95 % (by SDS-PAGE)
- Top Product
- Discover our top product FOLR1 Primärantikörper
-
-
- Applikationshinweise
-
Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
- Target
- FOLR1 (Folate Receptor 1 (Adult) (FOLR1))
- Andere Bezeichnung
- Folate Receptor alpha (FOLR1 Produkte)
- Synonyme
- FBP antikoerper, FOLR antikoerper, fbp antikoerper, folr antikoerper, folr1 antikoerper, FBP1 antikoerper, Folbp-1 antikoerper, Folbp1 antikoerper, Fbp1 antikoerper, FOLR1 antikoerper, Folr1 antikoerper, folate receptor 1 antikoerper, folate receptor 1 (adult) antikoerper, folate receptor 1 (adult) L homeolog antikoerper, zgc:165502 antikoerper, Folate receptor alpha antikoerper, folate receptor alpha antikoerper, FOLR1 antikoerper, folr1 antikoerper, folr1.L antikoerper, zgc:165502 antikoerper, Folr1 antikoerper, LOC100066084 antikoerper, LOC100725439 antikoerper
- Hintergrund
- Folate is an essential vitamin that must be obtained from food intake through intestinal absorption in mammals. Folate and reduced folic acid derivatives bind to the folate receptor (FR) family, which mediates the endocytosis of 5-methyltetrahydrofolate into the cell. The folate receptors consist of five members, α, β, γ, γ' (which is produced by alternative splicing) and δ. β-FR is attached to the membrane by a GPI anchor and is expressed in malignant tissues of epithelial and nonepithelial origin. γ-FR is expressed in tissues of hematopoietic origin, such as spleen, thymus and bone marrow. The expression pattern of δ-FR is elusive, which suggests that it is highly restricted both spatially and temporally. The α isoform of the folate receptor is used as a highly selective tumor marker and may be targeted for the delivery of therapeutic compounds to tumor cells by coupling to derivatives of folic acid.Synonyms: Adult folate-binding protein, FOLR, FOLR1, FR-alpha, Folate receptor 1, KB cells FBP, MOv18, Ovarian tumor-associated antigen MOv18
- Molekulargewicht
- approx. 34 kDa
- Gen-ID
- 2348
- NCBI Accession
- NP_000793
- UniProt
- P15328
- Pathways
- Dicarboxylic Acid Transport
-