CSPG5 Antikörper

Produktnummer ABIN499046

Produktdetails anti-CSPG5 Antikörper

Target: CSPG5 (Chondroitin Sulfate Proteoglycan 5 (Neuroglycan C) (CSPG5))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CSPG5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody detects endogenous levels of Neuroglycan C protein. (region surrounding Trp248)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Reinheit: > 95 % by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CSPG5

Target: CSPG5 (Chondroitin Sulfate Proteoglycan 5 (Neuroglycan C) (CSPG5))

Andere Bezeichnung: Neuroglycan C (CSPG5 Produkte)

Synonyme: CSPG5 antikoerper, cspg5 antikoerper, si:dkeyp-114f9.4 antikoerper, Caleb antikoerper, Ngc antikoerper, NGC antikoerper, CALEB antikoerper, chondroitin sulfate proteoglycan 5 antikoerper, chondroitin sulfate proteoglycan 5a antikoerper, chondroitin sulfate proteoglycan 5b antikoerper, CSPG5 antikoerper, cspg5a antikoerper, cspg5b antikoerper, Cspg5 antikoerper

Hintergrund: Neuroglycan C is a transmembrane chondroitin sulfate proteoglycan that is exclusively expressed in the central nervous system. NGC gene expression is developmentally regulated being altered by addiction to psychostimulants and by nerve lesion. Its core protein has a particular multidomain structure differing from those of other known proteoglycans, and this protein is modified post-translationally in various ways such as phosphorylation and glycosylation. Neuroglycan C is a novel part-time proteoglycan that changes its structure from a proteoglycan form to a non-proteoglycan form without chondroitin sulfate chains during the development of the cerebellum and retina. Evidence suggests that Neuroglycan C is involved in neuronal circuit formation in the central nervous system.Synonyms: Acidic leucine-rich EGF-like domain-containing brain protein, CALEB, CSPG5, Chondroitin sulfate proteoglycan 5, NGC

Molekulargewicht: approx. 60 kDa

Gen-ID: 10675

NCBI Accession: NP_006565

UniProt: O95196

Pathways: Glycosaminoglycan Metabolic Process