CNOT4 Antikörper

Produktnummer ABIN499042

Produktdetails anti-CNOT4 Antikörper

Target: CNOT4 (CCR4-NOT Transcription Complex Subunit 4 (CNOT4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CNOT4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of CNOT4 protein. (region surrounding Glu95)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Reinheit: > 95 % by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CNOT4

Target: CNOT4 (CCR4-NOT Transcription Complex Subunit 4 (CNOT4))

Andere Bezeichnung: CNOT4 (CNOT4 Produkte)

Synonyme: CLONE243 antikoerper, NOT4 antikoerper, NOT4H antikoerper, Not4 antikoerper, Not4h antikoerper, Not4hp antikoerper, CNOT4 antikoerper, CCR4-NOT transcription complex subunit 4 antikoerper, RNA binding (RRM/RBD/RNP motifs) family protein antikoerper, CCR4-NOT transcription complex, subunit 4 antikoerper, CCR4-NOT transcription complex subunit 4 L homeolog antikoerper, CCR4-NOT transcription complex, subunit 4b antikoerper, CNOT4 antikoerper, AT3G45630 antikoerper, Cnot4 antikoerper, cnot4.L antikoerper, cnot4b antikoerper

Hintergrund: CNOT4 (CCR4 NOT transcription complex subunit 4) has intrinsic E3 ubiquitin ligase activity. Binding of the CNOT4 RING finger to the ubiquitin-conjugating enzyme (E2) UbcH5B is highly selective. The CCR4-NOT complex functions as a global regulator of RNA polymerase II transcription.Synonyms: CCR4-NOT transcription complex subunit 4, CCR4-associated factor 4, E3 ubiquitin-protein ligase CNOT4, NOT4, NOT4Hp, Potential transcriptional repressor NOT4Hp

Molekulargewicht: approx. 52 kDa

Gen-ID: 4850

NCBI Accession: NP_001008226

UniProt: O95628