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Cofilin Antikörper (pSer3)
CFL1
Reaktivität: Human, Maus, Ratte
IHC (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-Cofilin Antikörper
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Target
Alle Cofilin (CFL1) Antikörper anzeigen
Cofilin (CFL1)
(Cofilin 1 (CFL1))
Bindungsspezifität
Alle Epitope für Cofilin Antikörper
pSer3
Reaktivität
Alle Reaktivitäten für Cofilin Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für Cofilin Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für Cofilin Antikörper
Polyklonal
Konjugat
Alle Konjugate für Cofilin Antikörper
Dieser Cofilin Antikörper ist unkonjugiert
Applikation
Alle Applikationen für Cofilin Antikörper
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Spezifität
This antibody detects endogenous levels of p-COFILN1 protein only when phosphorylated at Ser3.
Kreuzreaktivität (Details)
Species reactivity (expected):Mouse and Rat. Species reactivity (tested):Human.
Aufreinigung
Affinity chromatography
Reinheit
> 95 % by SDS-PAGE
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Discover our top product CFL1 Primärantikörper
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Anwendungsinformationen
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Applikationshinweise
Immunohistochemistry: 1/50 - 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
1,0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu Cofilin
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Target
Cofilin (CFL1)
(Cofilin 1 (CFL1))
Andere Bezeichnung
Cofilin-1 (CFL1 Produkte )
Synonyme
cfl1 antikoerper, xac1 antikoerper, xac2 antikoerper, cfl antikoerper, cb86 antikoerper, sb:cb86 antikoerper, zgc:56501 antikoerper, wu:fb18a04 antikoerper, wu:fk77b03 antikoerper, 12/8 antikoerper, ADF antikoerper, ADF/cofilin antikoerper, Adf antikoerper, CG4254 antikoerper, Cadf antikoerper, D-cof antikoerper, D61 antikoerper, Dmel\\CG4254 antikoerper, T8 antikoerper, Tsr antikoerper, cofilin antikoerper, cofilin/ADF antikoerper, cofilin/actin depolymerizing factor homolog antikoerper, l(2)03101 antikoerper, l(2)k03101 antikoerper, l(2)k05633 antikoerper, l(2)k13409 antikoerper, ntf antikoerper, CFL antikoerper, AA959946 antikoerper, Cof antikoerper, CFL1 antikoerper, cofilin 1 (non-muscle) L homeolog antikoerper, cofilin 1 (non-muscle) antikoerper, cofilin 1 (non-muscle), like antikoerper, cofilin 1 antikoerper, twinstar antikoerper, cofilin antikoerper, cofilin 1, non-muscle antikoerper, Contrafreeloading antikoerper, cfl1.L antikoerper, cfl1 antikoerper, cfl1l antikoerper, CFL1 antikoerper, tsr antikoerper, COF1 antikoerper, TSTA_042790 antikoerper, Cfl1 antikoerper, CFL antikoerper
Hintergrund
Cofilin, a member of the ADF/cofilin family is actually a protein with 70 % sequence homology to ADF, making it part of the ADF/cofilin family of small ADP-binding proteins. The protein binds to actin monomers and filaments, G actin and F actin, respectively. Cofilin causes depolymerization at the minus end of filaments, thereby preventing their reassembly. The protein is known to sever actin filaments by creating more positive ends on filament fragments. Cofilin/ADF(destrin) is likely to sever F-actin without capping and prefers ADP-actin. These monomers can be recycled by profilin, activating monomers to go back into filament form again by an ADP-to-ATP exchange. ATP-actin is then available for assembly.Synonyms: 18 kDa phosphoprotein, CFL, CFL1, Cofilin non-muscle isoform, p18
Molekulargewicht
approx. 19 kDa
Gen-ID
1072
NCBI Accession
NP_005498
UniProt
P23528
Pathways
Regulation of Cell Size , Tube Formation , Protein targeting to Nucleus , CXCR4-mediated Signaling Events
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