IL16 Antikörper

Produktnummer ABIN498681

Produktdetails anti-IL16 Antikörper

Target: IL16 (Interleukin 16 (IL16))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL16 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of IL-16 protein. (region surrounding Gly97)

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Reinheit: > 95 % by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu IL16

Target: IL16 (Interleukin 16 (IL16))

Andere Bezeichnung: Interleukin-16 / IL16 (IL16 Produkte)

Synonyme: IL16 antikoerper, LCF antikoerper, NIL16 antikoerper, PRIL16 antikoerper, prIL-16 antikoerper, mKIAA4048 antikoerper, IL-16 antikoerper, interleukin 16 antikoerper, IL16 antikoerper, Il16 antikoerper

Hintergrund: Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. They exert their biological effects through the binding of membrane-bound receptors which, in turn, intiate signal transduction cascades that elicit physiological changes in their target cells. Interleukin-16, or IL-16, is a cytokine that has chemoattractant activity on CD4+ T lymphocytes. It has long been known that eosinophils and CD4+ T lymphocytes are recruited to sites of allergic inflammation, but the molecular mechanism was poorly understood. IL-16, also referred to as lymphocyte chemoattractant factor, is secreted by activated eosinophils as part of the allergic response along with RANTES, an additional cytokine. Once bound to its cognate receptor, CD4, IL-16 initiates a signal cascade that results in the activation of the PKC family.Synonyms: IL-16, LCF, Lymphocyte chemoattractant factor

Gen-ID: 3603

NCBI Accession: NP_004504

UniProt: Q14005