Nerve Growth Factor Antikörper

Produktnummer ABIN498573

Produktdetails anti-Nerve Growth Factor Antikörper

Target: Nerve Growth Factor (NGF)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Nerve Growth Factor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of NGF protein. (region surrounding Leu82)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Nerve Growth Factor

Target: Nerve Growth Factor (NGF)

Andere Bezeichnung: NGF (NGF Produkte)

Synonyme: Beta-NGF antikoerper, HSAN5 antikoerper, NGFB antikoerper, Ngfb antikoerper, ngfb antikoerper, ns:zft386 antikoerper, xx:zft386 antikoerper, zgc:109730 antikoerper, beta-NGF antikoerper, hsan5 antikoerper, beta-ngf antikoerper, NGF antikoerper, ngf antikoerper, nerve growth factor antikoerper, nerve growth factor b (beta polypeptide) antikoerper, nerve growth factor S homeolog antikoerper, NGF antikoerper, Ngf antikoerper, ngfb antikoerper, ngf antikoerper, ngf.S antikoerper

Hintergrund: The prototype neurotrophin is nerve growth factor (NGF), originally discovered in the 1950s as a soluble peptide promoting the survival of, and neurite outgrowth from, sympathetic ganglia. Three additional structurally homologous neurotrophic factors have been identified. These include brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3) and neurotrophin-4 (NT-4) (also designated NT-5). These various neurotrophins stimulate the in vitro survival of distinct, but partially overlapping, populations of neurons. The cell surface receptors through which neurotrophins mediate their activity have been identified. For instance, the Trk A receptor is the preferential receptor for NGF, but also binds NT-3 and NT-4.Synonyms: Beta-NGF, Beta-nerve growth factor, NGFB

Molekulargewicht: approx. 27 kDa

Gen-ID: 4803

NCBI Accession: NP_002497

UniProt: P01138

Pathways: Regulation of Cell Size