Peroxiredoxin 3 Antikörper

Produktnummer ABIN498491

Produktdetails anti-Peroxiredoxin 3 Antikörper

Target: Peroxiredoxin 3 (PRDX3)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Peroxiredoxin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of PRX III protein. (region surrounding Lys93)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Reinheit: > 95 % by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Peroxiredoxin 3

Target: Peroxiredoxin 3 (PRDX3)

Andere Bezeichnung: Peroxiredoxin-3 / PRDX3 (PRDX3 Produkte)

Synonyme: cb718 antikoerper, wu:fk49e09 antikoerper, zgc:110282 antikoerper, zgc:112512 antikoerper, MGC83969 antikoerper, PRDX3 antikoerper, AOP-1 antikoerper, AOP1 antikoerper, HBC189 antikoerper, MER5 antikoerper, PRO1748 antikoerper, SP-22 antikoerper, prx-III antikoerper, AW822249 antikoerper, Aop1 antikoerper, D0Tohi1 antikoerper, Ef2l antikoerper, Mer5 antikoerper, Prx3 antikoerper, SP22 antikoerper, TDXM antikoerper, MTAP antikoerper, peroxiredoxin 3 antikoerper, peroxiredoxin 3 S homeolog antikoerper, peroxiredoxin PRX3 antikoerper, prdx3 antikoerper, PRDX3 antikoerper, prdx3.S antikoerper, PRX3 antikoerper, Prdx3 antikoerper

Hintergrund: The peroxiredoxin (PRX) family comprises six antioxidant proteins, PRX I, II, III, IV, V and VI, which protect cells from reactive oxygen species (ROS) by preventing the metalcatalyzed oxidation of enzymes. The PRX proteins primarily utilize thioredoxin as the electron donor for antioxidation, although they are fairly promiscuous with regard to the hydroperoxide substrate. In addition to protection from ROS, peroxiredoxins are also involved in cell proliferation, differentiation and gene expression. PRX I, II, IV and VI show diffuse cytoplasmic localization, while PRX III and V exhibit distinct mitochondrial localization. The human PRX I gene encodes a protein that is expressed in several tissues, including liver, kidney, testis, lung and nervous system. PRX II is expressed in testis, while PRX III shows expression in lung. PRX I, II and III are overexpressed in breast cancer and may be involved in its development or progression. Upregulated protein levels of PRX I and II in Alzheimer's disease (AD) and Down syndrome (DS) indicate the involvement of PRX I and II in their pathogenesis.Synonyms: AOP-1, AOP1, Antioxidant protein 1, HBC189, PRDX-3, PRX-III, Protein MER5 homolog, Prx-3, Prx3, Thioredoxin-dependent peroxide reductase mitochondrial

Molekulargewicht: approx. 22 kDa

Gen-ID: 10935

NCBI Accession: NP_006784

UniProt: P30048

Pathways: Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process