SOX8 Antikörper

Produktnummer ABIN498428

Produktdetails anti-SOX8 Antikörper

Target: SOX8 (SRY (Sex Determining Region Y)-Box 8 (SOX8))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOX8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of Sox-8/9/17/18 protein. (region surrounding Lys148)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Reinheit: > 95 % by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu SOX8

Target: SOX8 (SRY (Sex Determining Region Y)-Box 8 (SOX8))

Andere Bezeichnung: SOX8 (SOX8 Produkte)

Synonyme: SRY-box 8 antikoerper, SRY box 8 antikoerper, SRY-box 8 L homeolog antikoerper, SRY (sex determining region Y)-box 8 antikoerper, SOX8 antikoerper, Sox8 antikoerper, sox8.L antikoerper

Hintergrund: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at a minimum of 40 different loci that rapidly diverged in various animal lineages. At present 30 Sox genes have been identified, and members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.Synonyms: SOX-17, SOX-18, SOX-8, SOX-9

Molekulargewicht: approx. 47 kDa

Gen-ID: 30812

NCBI Accession: NP_055402

UniProt: P57073

Pathways: Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development