FOXL1 Antikörper

Produktnummer ABIN498334

Produktdetails anti-FOXL1 Antikörper

Target: FOXL1 (Forkhead Box L1 (FOXL1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of FoxL1 protein. (region surrounding Gly150)

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography using epitope-specific immunogen

Reinheit: > 95 % (by SDS-PAGE)

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu FOXL1

Target: FOXL1 (Forkhead Box L1 (FOXL1))

Andere Bezeichnung: FOXL1 / FKHL11 (FOXL1 Produkte)

Synonyme: zgc:63595 antikoerper, FOXL1 antikoerper, fkh6 antikoerper, fkhl11 antikoerper, freac7 antikoerper, CG1132 antikoerper, Dmel\\CG1132 antikoerper, Dmfd2 antikoerper, FD2 antikoerper, FoxL1 antikoerper, fd2 antikoerper, Foxl1 antikoerper, FKH6 antikoerper, FKHL11 antikoerper, FREAC7 antikoerper, Fkh6 antikoerper, fkh-6 antikoerper, forkhead box L1 antikoerper, forkhead domain 64A antikoerper, forkhead transcription factor L1 antikoerper, forkhead box L1 transcription factor antikoerper, foxl1 antikoerper, FOXL1 antikoerper, fd64A antikoerper, LOC579718 antikoerper, Foxl1 antikoerper

Hintergrund: FOXL1 is a 337 amino acid protein encoded by the mouse gene Foxl1. FOXL1 belongs to the fork head family and contains one fork head DNA-binding domain. The HNF3/fork head family includes a large number of transcription factors that share a structurally related DNA binding domain. Fork head factors are known to play important roles both during development and in adults. FOXL1 is a winged helix transcriptional regulator expressed in the mesenchymal layer of developing and mature gastrointestinal tract. FOXL1- deficient mice exhibit various defects not only in the epithelial layer of the gastrointestinal tract but also in gut-associated lymphoid tissues. In the small intestine of FOXL1-deficient mice, the formation of Peyer's patches is affected, particularly in the caudal region. FOXL1 is a mesenchymal modifier of the adenomatous polyposis coli (APC) gene products and plays a key role in gastrointestinal tumorigenesis.Synonyms: FREAC7, Forkhead box protein L1, Forkhead-related protein FKHL11, Forkhead-related transcription factor 7

Molekulargewicht: approx. 36 kDa

Gen-ID: 2300

NCBI Accession: NP_005241

UniProt: Q12952