ELAVL2 Antikörper

Produktnummer ABIN498332

Produktdetails anti-ELAVL2 Antikörper

Target: ELAVL2 (ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 2 (Hu Antigen B) (ELAVL2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ELAVL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody detects endogenous levels of Hel-N1 protein. (region surrounding Ser27)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography using epitope-specific immunogen

Reinheit: > 95 % (by SDS-PAGE)

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu ELAVL2

Target: ELAVL2 (ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 2 (Hu Antigen B) (ELAVL2))

Andere Bezeichnung: ELAVL2 / HUB (ELAVL2 Produkte)

Synonyme: ELAVL2 antikoerper, HEL-N1 antikoerper, HELN1 antikoerper, HUB antikoerper, Hub antikoerper, mel-N1 antikoerper, Elav2 antikoerper, Xel-1 antikoerper, el-1 antikoerper, elavl2 antikoerper, elrB antikoerper, hel-n1 antikoerper, heln1 antikoerper, hub antikoerper, p45 antikoerper, zgc:91918 antikoerper, ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B) antikoerper, ELAV like RNA binding protein 2 antikoerper, ELAV like neuron-specific RNA binding protein 2 L homeolog antikoerper, ELAV like neuron-specific RNA binding protein 2 antikoerper, ELAVL2 antikoerper, Elavl2 antikoerper, elavl2.L antikoerper, elavl2 antikoerper

Hintergrund: The Elav-like genes encode for a family of RNA-binding proteins. Elav, a Drosophila protein and the first described member, is expressed immediately after neuroblastic differentiation into neurons and is necessary for neuronal differentiation and maintenance. Several mammalian Elav-like proteins, designated HuC, HuD and Hel-N1, are also expressed in postmitotic neurons. An additional mammalian homolog, HuR, which is also designated HuA, is ubiquitously expressed and is also overexpressed in a wide variety of tumors. Characteristically, these homologs all contain three RNA recognition motifs (RRM), and they specifically bind to AU-rich elements (ARE) in the 3'-untranslated region of mRNAs transcripts. ARE sites target mRNA for rapid degradation and thereby regulate the expression levels of genes involved in cell growth and differentiation.Synonyms: ELAV-like neuronal protein 1, ELAV-like protein 2, Hel-N1, Hu-antigen B, Nervous system-specific RNA-binding protein Hel-N1

Molekulargewicht: approx. 38 kDa

Gen-ID: 1993

NCBI Accession: NP_004423

UniProt: Q12926