GTF2A1 Antikörper

Produktnummer ABIN498320

Produktdetails anti-GTF2A1 Antikörper

Target: GTF2A1 (General Transcription Factor IIA, 1, 19/37kDa (GTF2A1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GTF2A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of TFIIA-α protein. (region surrounding Glu311)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography using epitope-specific immunogen

Reinheit: > 95 % (by SDS-PAGE)

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu GTF2A1

Target: GTF2A1 (General Transcription Factor IIA, 1, 19/37kDa (GTF2A1))

Andere Bezeichnung: GTF2A1 / TF2A1 (GTF2A1 Produkte)

Synonyme: gtf2a1 antikoerper, tf2a1 antikoerper, tfiia antikoerper, tfiiaa/b antikoerper, tfiiaa/b-2 antikoerper, tf2a antikoerper, fc15h02 antikoerper, fj36b10 antikoerper, zgc:55847 antikoerper, wu:fc15h02 antikoerper, wu:fj36b10 antikoerper, GTF2A1 antikoerper, tfiiaa/b-1 antikoerper, 6330549H03Rik antikoerper, AA536742 antikoerper, AA959775 antikoerper, AW060250 antikoerper, TfIIAa/b antikoerper, Tfiia1 antikoerper, Tf2a antikoerper, TfIIa antikoerper, TF2A1 antikoerper, TFIIA antikoerper, TFIIA-42 antikoerper, TFIIAL antikoerper, general transcription factor IIA subunit 1 antikoerper, general transcription factor IIA 1 L homeolog antikoerper, general transcription factor IIA, 1 antikoerper, general transcription factor IIA 1 antikoerper, general transcription factor IIA 1 S homeolog antikoerper, general transcription factor II A, 1 antikoerper, general transcription factor 2A subunit 1 antikoerper, GTF2A1 antikoerper, gtf2a1.L antikoerper, gtf2a1 antikoerper, gtf2a1.S antikoerper, Gtf2a1 antikoerper

Hintergrund: Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFIIH. Recognition of the TATA binding element by TBP, one of the first steps in transcription initiation, may be regulated by TFIIA. TFIIA consists of three subunits designated TFIIA-α, TFIIA-β and TFIIA-γ, and it interacts with both TBP and a TAF (TBP-associated factor). It has been demonstrated that the basic region of TBP is essential for TFIIA-dependent function of TBP.Synonyms: General transcription factor IIA subunit 1, TFIIA-42, TFIIAL, Transcription initiation factor IIA subunit 1

Molekulargewicht: approx. 42 kDa

Gen-ID: 2957

NCBI Accession: NP_056943

UniProt: P52655