CKMT2 Antikörper

Produktnummer ABIN498310

Produktdetails anti-CKMT2 Antikörper

Target: CKMT2 (Creatine Kinase, Mitochondrial 2 (Sarcomeric) (CKMT2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CKMT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of sMtCK protein. (region surrounding Trp262)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography using epitope-specific immunogen

Reinheit: > 95 % (by SDS-PAGE)

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu CKMT2

Target: CKMT2 (Creatine Kinase, Mitochondrial 2 (Sarcomeric) (CKMT2))

Andere Bezeichnung: CKMT2 (CKMT2 Produkte)

Synonyme: 2300008A19Rik antikoerper, ScCKmit antikoerper, MIBCK antikoerper, SMTCK antikoerper, ckmt2-2 antikoerper, zgc:73059 antikoerper, CKMT2 antikoerper, Mib-CK antikoerper, S-MtCK antikoerper, creatine kinase, mitochondrial 2 antikoerper, creatine kinase, mitochondrial 2 (sarcomeric) antikoerper, creatine kinase, mitochondrial 2b (sarcomeric) antikoerper, CKMT2 antikoerper, ckmt2 antikoerper, Ckmt2 antikoerper, ckmt2b antikoerper

Hintergrund: CKMT2 belongs to the creatine kinase isoenzyme family, and is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It exists as two isoenzymes, sarcomeric CKMT2 and ubiquitous CKMT2, which are encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80 % homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.Synonyms: Basic-type mitochondrial creatine kinase, Creatine kinase S, Mib-CK, S-MtCK, sarcomeric mitochondrial Creatine kinase

Molekulargewicht: approx. 45 kDa

Gen-ID: 1160

NCBI Accession: NP_001093205

UniProt: P17540