KIF11 Antikörper

Produktnummer ABIN498151

Produktdetails anti-KIF11 Antikörper

Target: KIF11 (Kinesin Family Member 11 (KIF11))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIF11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of Eg5 protein.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography using epitope-specific immunogen

Reinheit: > 95 % (by SDS-PAGE)

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu KIF11

Target: KIF11 (Kinesin Family Member 11 (KIF11))

Andere Bezeichnung: KIF11 (KIF11 Produkte)

Synonyme: EG5 antikoerper, HKSP antikoerper, KNSL1 antikoerper, MCLMR antikoerper, TRIP5 antikoerper, Eg5 antikoerper, Kif8 antikoerper, Kifl1 antikoerper, Knsl1 antikoerper, F2H17.19 antikoerper, F2H17_19 antikoerper, DDBDRAFT_0189194 antikoerper, DDBDRAFT_0201556 antikoerper, DDB_0189194 antikoerper, DDB_0201556 antikoerper, XLEg5K1 antikoerper, XlEg5 antikoerper, cos2 antikoerper, costal2 antikoerper, eg5 antikoerper, hksp antikoerper, kif11 antikoerper, kif11-a antikoerper, kif11-b antikoerper, kif11b antikoerper, knsl1 antikoerper, trip5 antikoerper, Cos2 antikoerper, Costal2 antikoerper, XLEg5K2 antikoerper, kif11a antikoerper, kinesin family member 11 antikoerper, P-loop containing nucleoside triphosphate hydrolases superfamily protein antikoerper, kinesin family member 11 S homeolog antikoerper, kinesin family member 11 L homeolog antikoerper, KIF11 antikoerper, Kif11 antikoerper, AT2G36200 antikoerper, kif11 antikoerper, kif11.S antikoerper, kif11.L antikoerper

Hintergrund: Eukaryotes contain a superfamily of microtubule-based motor proteins comprising Kinesin and a number of related proteins that are thought to participate in various forms of intracellular motility, including cell division and organelle transport. Eg5 (also known as Kinesin-like protein KIF11 or TRIP5) is a slow, plus-end-directed microtubule-based motor of the BimC kinesin family that is essential for bipolar spindle formation during eukaryotic cell division. When the expression of Eg5 is blocked, centrosome migration halts and cells are arrested in mitosis with monoastral microtubule arrays. Eg5 is phosphorylated on serine during S phase and on both serine and Thr 927 during mitosis, which regulates the association of Eg5 with the spindle apparatus (probably during early prophase). Eg5 is also known to be a member of the thyroid receptor interacting protein (TRIP) family, and interacts with the thyroid hormone receptor only in the presence of thyroid hormone.Synonyms: EG5, KIF11, KNSL1, Kinesin-like protein 1, Kinesin-like protein KIF11, Kinesin-like spindle protein HKSP, Kinesin-related motor protein Eg5, TRIP-5, TRIP5, Thyroid receptor-interacting protein 5

Molekulargewicht: approx. 119 kDa

Gen-ID: 3832

NCBI Accession: NP_004514

UniProt: P52732