HAT1 Antikörper

Produktnummer ABIN498132

Produktdetails anti-HAT1 Antikörper

Target: HAT1 (Histone Acetyltransferase 1 (HAT1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HAT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody detects endogenous levels of HAT1 protein.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography using epitope-specific immunogen

Reinheit: > 95 % (by SDS-PAGE)

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu HAT1

Target: HAT1 (Histone Acetyltransferase 1 (HAT1))

Andere Bezeichnung: HAT1 (HAT1 Produkte)

Synonyme: KAT1 antikoerper, HAC07 antikoerper, HAC7 antikoerper, HAG02 antikoerper, MIK19.19 antikoerper, MIK19_19 antikoerper, histone acetyltransferase of the GNAT family 2 antikoerper, hac106 antikoerper, hat1 antikoerper, zgc:92639 antikoerper, histone acetyltransferase 1 antikoerper, histone acetyltransferase of the GNAT family 2 antikoerper, histone acetyltransferase catalytic subunit antikoerper, histone acetyltransferase Hat1 antikoerper, histone acetyltransferase 1 L homeolog antikoerper, HAT1 antikoerper, Hat1 antikoerper, HAG2 antikoerper, hat1 antikoerper, hat1.L antikoerper

Hintergrund: In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (p300/CBPassociated factor), p300/CBP, HAT1, and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated RPD3) and HDAC3-6, have been identified as histone deacetylases.Synonyms: Histone acetyltransferase type B catalytic subunit

Molekulargewicht: approx. 49 kDa

Gen-ID: 8520

NCBI Accession: NP_003633

UniProt: O14929