ATP1A1 Antikörper

Produktnummer ABIN498101

Produktdetails anti-ATP1A1 Antikörper

Target: ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP1A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody antibody detects endogenous levels of Na(+)/K(+)-ATPase alpha1 protein.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen.

Anwendungsinformationen

Applikationshinweise: Western Blots: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200. Immunofluorescence: 1/100approx. 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ATP1A1

Target: ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))

Andere Bezeichnung: ATP1A1 (ATP1A1 Produkte)

Synonyme: Atpa-1 antikoerper, BC010319 antikoerper, Nkaa1b antikoerper, K-ATPase antikoerper, Na+K+ATPase antikoerper, atp1a1 antikoerper, atp1a1a.1 antikoerper, atp1a1l1 antikoerper, atp[a]1B1 antikoerper, cb70 antikoerper, wu:fa03c03 antikoerper, wu:fb92h10 antikoerper, atp1a1l5 antikoerper, atp[a]1B2 antikoerper, cb707 antikoerper, wu:fj34g01 antikoerper, zgc:92351 antikoerper, ATPase Na+/K+ transporting subunit alpha 1 antikoerper, ATPase, Na+/K+ transporting, alpha 1 polypeptide antikoerper, ATPase Na+/K+ transporting subunit alpha 1 L homeolog antikoerper, ATPase, Na+/K+ transporting, alpha 1a polypeptide, tandem duplicate 1 antikoerper, ATPase, Na+/K+ transporting, alpha 1b polypeptide antikoerper, ATP1A1 antikoerper, Atp1a1 antikoerper, atp1a1.L antikoerper, atp1a1a.1 antikoerper, atp1a1b antikoerper

Hintergrund: The sodium/potassium ATPase is an integral membrane enzyme found in all cells of higher organisms and is responsible for the ATP dependent transport of sodium and potassium across the cell membrane. This membrane bound enzyme is related to a number of other ATPases including sarcoplasmic and endoplasmic reticulum calcium ATPase (SERCA) and plasma membrane calcium ATPase (PMCA). The sodium / potassium ATPase consists of a large, multipass, transmembrane catalytic subunit, termed the alpha subunit, and an associated smaller glycoprotein, termed the beta subunit. Studies indicate that there are three isoforms of the alpha subunit (alpha 1, alpha 2, alpha 3) and two isoforms of the beta subunit (beta 1 and beta 2) encoded by two multigene families.The different isoforms of the sodium / potassium ATPase exhibit tissue specific and developmental patterns of expression. The alpha 1 and beta mRNAs are present in all cell types examined, whereas the alpha 2 and alpha 3 mRNAs exhibit a more restricted pattern of cell specific expression. The alpha subunit has been found in kidney, brain, heart, and to a lesser extent liver, skeletal and smooth muscle.Synonyms: Na(+)/K(+) ATPase alpha-1 subunit, Sodium pump ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit alpha-1

Molekulargewicht: approx. 112 kDa

Gen-ID: 476

NCBI Accession: NP_000692

UniProt: P05023

Pathways: Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Proton Transport, Ribonucleoside Biosynthetic Process