CCKAR Antikörper

Produktnummer ABIN498009

Produktdetails anti-CCKAR Antikörper

Target: CCKAR (Cholecystokinin A Receptor (CCKAR))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCKAR Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Reacts with Cholecystokinin A Receptor (CCKAR).

Kreuzreaktivität (Details): Species reactivity (expected):Monkey, Rat, Guinea pig.
Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: CCKAR antibody was raised against synthetic peptide from human CCKAR. .Remarks: Mouse Identity: 45% Mouse Similarity: 55% Rat Identity: 80% Rat Similarity: 90%

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on Formalin Fixed Paraffin Embedded Tissues: 10 μg/mL (Requirespretreatment with Proteinase K).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Details zu CCKAR

Target: CCKAR (Cholecystokinin A Receptor (CCKAR))

Andere Bezeichnung: CCK-A Receptor (CCKAR Produkte)

Synonyme: CCK-XL antikoerper, cck-a antikoerper, cck1-r antikoerper, cckar-A antikoerper, cckbr antikoerper, cckra antikoerper, CCKAR antikoerper, CCK-A antikoerper, CCK1-R antikoerper, CCKRA antikoerper, AW106902 antikoerper, Cck-ar antikoerper, CCK-AR antikoerper, cholecystokinin A receptor antikoerper, cholecystokinin A receptor L homeolog antikoerper, CCKAR antikoerper, cckar.L antikoerper, Cckar antikoerper

Hintergrund: The cholecystokinin (CCK) family of peptide hormones have been implicated in numerous important physiologic events. These appear to be mediated through 2 general classes of receptors, A (CCKAR)and B (CCKBR), based on their binding affinities for CCK/gastrin family peptides. Through binding to class A receptors, CCK is a major physiologic mediator of gallbladder contraction and pancreatic enzyme secretion. It appears to play a role in slowing gastric emptying, relaxation of the sphincter of Oddi, and potentiation of insulin secretion. Further, it has been implicated as a mediator of pancreatic growth and tumorigenesis. Class A receptors have also been described in the anterior pituitary, myenteric plexus, and regions of the central nervous system, where they have been implicated in the pathogenesis of feeding disorders, Parkinson disease, schizophrenia, and drug addiction.Synonyms: CCKA Receptor, CCKAR, CCKRA, Cholecystokinin receptor type A, Cholecystokinin-1 receptor

Gen-ID: 886

NCBI Accession: NP_000721

UniProt: P32238

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Feeding Behaviour