PCSK7 Antikörper (AA 692-721)

Produktnummer ABIN3032338

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PCSK7 in ELISA und WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PCSK7 Antikörper (AA 692-721) (ABIN3032338)

Target: PCSK7 (Proprotein Convertase Subtilisin/kexin Type 7 (PCSK7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCSK7 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-PCSK7 Antikörper

Bindungsspezifität: AA 692-721

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 692-721 from the human protein was used as the immunogen for this PCSK7 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the PCSK7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the PCSK7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu PCSK7

Target: PCSK7 (Proprotein Convertase Subtilisin/kexin Type 7 (PCSK7))

Andere Bezeichnung: PCSK7

Hintergrund: The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease. It is structurally related to its family members, PACE and PACE4. This protein is concentrated in the trans-Golgi network, associated with the membranes, and is not secreted. It can process proalbumin and is thought to be responsible for the activation of HIV envelope glycoproteins gp160 and gp140. This gene has been implicated in the transcriptional regulation of housekeeping genes. Multiple alternatively spliced transcripts are described for this gene but their full length nature is not yet known. Downstream of this gene's map location at 11q23-q24, nucleotides that match part of this gene's 3' end are duplicated and inverted. A translocation breakpoint associated with lymphoma occurs between this gene and its inverted counterpart.

UniProt: Q16549