EPHA1 Antikörper (N-Term)

Produktnummer ABIN3030827

Produktdetails anti-EPHA1 Antikörper

Target: EPHA1 (Ephrin Type A Receptor 1 (EPHA1))

Bindungsspezifität: AA 70-105, N-Term

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPHA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antigen affinity purified

Immunogen: This mouse Epha1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 70-105 amino acids from the N-terminal region of mouse Epha1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the Epha1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Epha1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu EPHA1

Target: EPHA1 (Ephrin Type A Receptor 1 (EPHA1))

Andere Bezeichnung: Epha1 (EPHA1 Produkte)

Synonyme: EPH antikoerper, EPHT antikoerper, EPHT1 antikoerper, 5730453L17Rik antikoerper, AL033318 antikoerper, Eph antikoerper, Esk antikoerper, EPHA9 antikoerper, EPH receptor A1 antikoerper, Eph receptor A1 antikoerper, EPHA1 antikoerper, Epha1 antikoerper

Hintergrund: Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand. Upon activation by EFNA1 induces cell attachment to the extracellular matrix inhibiting cell spreading and motility through regulation of ILK and downstream RHOA and RAC. Plays also a role in angiogenesis and regulates cell proliferation. May play a role in apoptosis.

UniProt: Q60750