TNFRSF21 Antikörper (AA 356-385)

Produktnummer ABIN3029370

Produktdetails anti-TNFRSF21 Antikörper

Target: TNFRSF21 (Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21))

Bindungsspezifität: AA 356-385

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNFRSF21 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität (Details): Expected species reactivity: Mouse, Rat

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 356-385 from the human protein was used as the immunogen for this DR6 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the DR6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the DR6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu TNFRSF21

Target: TNFRSF21 (Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21))

Andere Bezeichnung: DR6 (Death Receptor 6) (TNFRSF21 Produkte)

Synonyme: TNFRSF21 antikoerper, tnfrsf21 antikoerper, MGC146356 antikoerper, BM-018 antikoerper, CD358 antikoerper, DR6 antikoerper, AA959878 antikoerper, R74815 antikoerper, TR7 antikoerper, dr6 antikoerper, im:6795346 antikoerper, wu:fa55e01 antikoerper, wu:fb02e11 antikoerper, wu:fc29a09 antikoerper, wu:fi27h08 antikoerper, TNF receptor superfamily member 21 antikoerper, tumor necrosis factor receptor superfamily member 21 antikoerper, tumor necrosis factor receptor superfamily, member 21 antikoerper, TNFRSF21 antikoerper, tnfrsf21 antikoerper, Tnfrsf21 antikoerper

Hintergrund: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation.

UniProt: O75509

Pathways: Regulation of Lipid Metabolism by PPARalpha