Titration of the BMPR1B antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the BMPR1B antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
BMPR1B
(Bone Morphogenetic Protein Receptor, Type IB (BMPR1B))
ALK6 antikoerper, BMPR-IB antikoerper, FecB antikoerper, alk-6 antikoerper, alk6 antikoerper, cdw293 antikoerper, alk6b antikoerper, zgc:172219 antikoerper, BMPR1B antikoerper, AI385617 antikoerper, ALK-6 antikoerper, AV355320 antikoerper, Acvrlk6 antikoerper, Alk6 antikoerper, BMPR-1B antikoerper, CFK-43a antikoerper, SKR6 antikoerper, BR1b antikoerper, alk6tr antikoerper, bmpr1b antikoerper, zALK-6 antikoerper, zgc:92220 antikoerper, CDw293 antikoerper, BMP15 antikoerper, BMPRIB antikoerper, RPK-1 antikoerper, bone morphogenetic protein receptor type 1B antikoerper, bone morphogenetic protein receptor, type IBb antikoerper, bone morphogenetic protein receptor, type 1B antikoerper, bone morphogenetic protein receptor, type IBa antikoerper, BMPR1B antikoerper, bmpr1b antikoerper, bmpr1bb antikoerper, Bmpr1b antikoerper, bmpr1ba antikoerper
Hintergrund
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension.