PKC alpha Antikörper
Kurzübersicht für PKC alpha Antikörper (ABIN4953283)
Target
Alle PKC alpha (PKCa) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- PKC alpha Antibody / aPKC
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Kreuzreaktivität (Details)
- Expected species reactivity: Human
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Aufreinigung
- Protein G affinity
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Immunogen
- A synthetic PKC alpha/aPKC peptide was used as the immunogen for the PKC alpha antibody.
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Isotyp
- IgG2a
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Applikationshinweise
- The stated application concentrations are suggested starting points. Titration of the PKC alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In PBS with 50 % glycerol and 0.03 % ProClin 300
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store the PKC alpha antibody at -20oC.
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- PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))
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Andere Bezeichnung
- PKC alpha
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Hintergrund
- This is a calcium-activated, phospholipid-dependent, serine- and threonine-specific enzyme. May play a role in cell motility by phosphorylating CSPG4. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
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UniProt
- P17252
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Pathways
- WNT Signalweg, T-Zell Rezeptor Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
Target
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