PKC alpha Antikörper

Produktnummer ABIN4953283

Der Maus Monoklonal anti-PKC alpha Antikörper wird verwendet zum Nachweis von PKC alpha in Proben von Ratte und Primate. Er wurde validiert für WB.

Kurzübersicht für PKC alpha Antikörper (ABIN4953283)

Target: PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))

Reaktivität: Ratte, Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PKC alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 3G11-G11-G11

Produktdetails anti-PKC alpha Antikörper

Kreuzreaktivität (Details): Expected species reactivity: Human

Aufreinigung: Protein G affinity

Immunogen: A synthetic PKC alpha/aPKC peptide was used as the immunogen for the PKC alpha antibody.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the PKC alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300

Lagerung: -20 °C

Informationen zur Lagerung: Store the PKC alpha antibody at -20°C.

Details zu PKC alpha

Target: PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))

Andere Bezeichnung: PRKCA / PKC alpha

Hintergrund: This is a calcium-activated, phospholipid-dependent, serine- and threonine-specific enzyme. May play a role in cell motility by phosphorylating CSPG4. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.

UniProt: P17252

Pathways: WNT Signalweg, T-Zell Rezeptor Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling