DLG1
Reaktivität: Human
WB, ELISA
Wirt: Maus
Monoclonal
1D8
unconjugated
Applikationshinweise
Optimal dilution of the SAP97 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Lagerung
-20 °C
Informationen zur Lagerung
After reconstitution, the SAP97 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
DLG1 antikoerper, Dlgh1 antikoerper, SAP97 antikoerper, B130052P05Rik antikoerper, E-dlg/SAP97 antikoerper, SAP-97 antikoerper, mKIAA4187 antikoerper, DLGH1 antikoerper, dJ1061C18.1.1 antikoerper, hdlg antikoerper, discs large MAGUK scaffold protein 1 antikoerper, discs, large homolog 1 (Drosophila) antikoerper, DLG1 antikoerper, Dlg1 antikoerper
Hintergrund
Disks large homolog 1 (DLG1), also known as synapse-associated protein 97 or SAP97, is a protein that in humans is encoded by the SAP97 gene. SAP97 is expressed throughout the body in epithelial cells, including the kidney and brain. There is some evidence that SAP97 regulates cell-to-cell adhesion during cell death, and may interact with HPV. In the brain, SAP97's function is involved in the trafficking of transmembrane receptors from the ER to the plasma membrane. SAP97's function has been investigated by reducing its expression by knockout or increasing its expression heterologously. Mice in which the SAP97 gene has been knocked out die perinatally, have a cleft palate, and deficiencies in renal function. Overexpression of SAP97 in mammalian neurons leads to increased synaptic strength.