NRIP1 Antikörper

Produktnummer ABIN4952410

Produktdetails anti-NRIP1 Antikörper

Target: NRIP1 (Nuclear Receptor Interacting Protein 1 (NRIP1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NRIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: Amino acids EAHLQQYSREHALKTQNANQAASERLAAMARLQE of human RIP140/NRIP1 were used as the immunogen for the RIP140 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the RIP140 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the RIP140 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu NRIP1

Target: NRIP1 (Nuclear Receptor Interacting Protein 1 (NRIP1))

Andere Bezeichnung: RIP140 / NRIP1 (NRIP1 Produkte)

Synonyme: MGC68665 antikoerper, NRIP1 antikoerper, RIP140 antikoerper, 6030458L20Rik antikoerper, 8430438I05Rik antikoerper, 9630050P12 antikoerper, AA959574 antikoerper, AW456757 antikoerper, nuclear receptor interacting protein 1 S homeolog antikoerper, nuclear receptor interacting protein 1 antikoerper, circumsporozoite protein antikoerper, nrip1.S antikoerper, NRIP1 antikoerper, nrip1 antikoerper, Nrip1 antikoerper, LOC100627733 antikoerper

Hintergrund: Nuclear receptor-interacting protein 1 (NRIP1), also known as receptor-interacting protein 140 (RIP140), is a protein that in humans is encoded by the NRIP1 gene. It is a nuclear protein that specifically interacts with the hormone-dependent activation domain AF2 of nuclear receptors. Also known as RIP140, this protein is a key regulator which modulates transcriptional activity of a variety of transcription factors, including the estrogen receptor. RIP140 has an important role in regulating lipid and glucose metabolism, and regulates gene expression in metabolic tissues including heart, skeletal muscle, and liver. A major role for RIP140 in adipose tissue is to block the expression of genes involved in energy dissipation and mitochondrial uncoupling, including uncoupling protein 1 and carnitine palmitoyltransferase 1b.

UniProt: P48552

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway