Optimal dilution of the RAP1A antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Lagerung
-20 °C
Informationen zur Lagerung
After reconstitution, the RAP1A antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Target
RAP1A
(RAP1A, Member of RAS Oncogene Family (RAP1A))
KREV-1 antikoerper, KREV1 antikoerper, RAP1 antikoerper, SMGP21 antikoerper, AI848598 antikoerper, G-22K antikoerper, Krev-1 antikoerper, Rap1 antikoerper, RAP-1A antikoerper, rap 1A antikoerper, wu:fc66g06 antikoerper, zgc:86676 antikoerper, krev-1 antikoerper, krev1 antikoerper, rap1 antikoerper, RAP1A, member of RAS oncogene family antikoerper, RAS-related protein 1a antikoerper, RAP1A, member of RAS oncogene family a antikoerper, RAP1A, member of RAS oncogene family L homeolog antikoerper, RAP1A antikoerper, Rap1a antikoerper, rap1aa antikoerper, rap1a.L antikoerper
Hintergrund
Ras-related protein Rap-1A is a protein that in humans is encoded by the RAP1A gene. This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. And it is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. Additionally, the encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants.