HRPT2 Antikörper (AA 119-520)

Produktnummer ABIN4951356

Produktdetails anti-HRPT2 Antikörper

Target: HRPT2 (CDC73) (Parafibromin (CDC73))

Bindungsspezifität: AA 119-520

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HRPT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: Amino acids 119-520 of human HRPT2 were used as the immunogen for the HRPT2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the HRPT2 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the HRPT2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu HRPT2

Target: HRPT2 (CDC73) (Parafibromin (CDC73))

Andere Bezeichnung: HRPT2 / CDC73 (CDC73 Produkte)

Synonyme: C1orf28 antikoerper, HPTJT antikoerper, HRPT2 antikoerper, HYX antikoerper, 8430414L16Rik antikoerper, BC027756 antikoerper, C130030P16Rik antikoerper, C81219 antikoerper, Hrpt2 antikoerper, hrpt2 antikoerper, zgc:63956 antikoerper, MGC108428 antikoerper, cdc73 antikoerper, LOC100222932 antikoerper, cell division cycle 73 antikoerper, cell division cycle 73, Paf1/RNA polymerase II complex component antikoerper, cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) antikoerper, parafibromin antikoerper, cell division cycle 73 S homeolog antikoerper, CDC73 antikoerper, Cdc73 antikoerper, cdc73 antikoerper, Tsp_03925 antikoerper, Tsp_04052 antikoerper, Tsp_04125 antikoerper, cdc73.S antikoerper

Hintergrund: Cell division cycle 73, also known as HRPT2, is a protein which in humans is encoded by the CDC73 gene. This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. And this protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.

UniProt: Q6P1J9

Pathways: Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance