DMRT1
Reaktivität: Human
ELISA
Wirt: Kaninchen
Polyclonal
HRP
Applikationshinweise
Optimal dilution of the DMRT1 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Lagerung
-20 °C
Informationen zur Lagerung
After reconstitution, the DMRT1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Target
DMRT1
(Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))
DMT1 antikoerper, DMRT1 antikoerper, zgc:136676 antikoerper, dmrt1 antikoerper, dmrt1-alpha antikoerper, dmt1 antikoerper, dmrt1-beta antikoerper, xdmrt1 antikoerper, doublesex and mab-3 related transcription factor 1 antikoerper, doublesex and mab-3 related transcription factor 1 L homeolog antikoerper, doublesex and mab-3 related transcription factor 1 S homeolog antikoerper, DMRT1 antikoerper, Dmrt1 antikoerper, dmrt1 antikoerper, dmrt1.L antikoerper, dmrt1.S antikoerper
Hintergrund
Doublesex and mab-3 related transcription factor 1, also known as DMRT1, is a protein which in humans is encoded by the DMRT1 gene. This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.