KIAA1524 Antikörper

Produktnummer ABIN4950567

Produktdetails anti-KIAA1524 Antikörper

Target: KIAA1524

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIAA1524 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: Amino acids EVQKAQLEGRLEEKESLVKLQQEELNKHSHMIAMIH of human KIAA1524 were used as the immunogen for the CIP2A antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CIP2A antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the CIP2A antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu KIAA1524

Target: KIAA1524

Andere Bezeichnung: CIP2A / KIAA1524 (KIAA1524 Produkte)

Synonyme: CIP2A antikoerper, p90 antikoerper, AA408511 antikoerper, AU018569 antikoerper, Cip2a antikoerper, Kiaa1524 antikoerper, KIAA1524 antikoerper, LOC100222895 antikoerper, RGD1310335 antikoerper, cell proliferation regulating inhibitor of protein phosphatase 2A antikoerper, RIKEN cDNA C330027C09 gene antikoerper, KIAA1524 antikoerper, cell proliferation regulating inhibitor of protein phosphatase 2A L homeolog antikoerper, CONSTANS interacting protein 2a antikoerper, CIP2A antikoerper, C330027C09Rik antikoerper, KIAA1524 antikoerper, cip2a.L antikoerper, CIP2a antikoerper, cip2a antikoerper, Cip2a antikoerper

Hintergrund: Protein CIP2A, also known as 'cancerous inhibitor of PP2A' and p90, is a protein that in humans is encoded by the KIAA1524 gene. It is required for the malignant cellular growth and for in vivo tumor formation. In accordance with the oncogenic role of CIP2A, overexpression promotes Ras-elicited cell growth and transforms immortalized human cells (HEK-TERVs). More recently CIP2A has been shown to regulate phosphorylation and activity of many other oncoproteins and to drive malignant cell growth and tumorigenesis in various human cancer types. Importantly, CIP2A deficient mice are viable, suggesting that targeting of oncogenic function of CIP2A would not result in serious side-effects.

UniProt: Q8TCG1