CD58 Antikörper
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- Target Alle CD58 Antikörper anzeigen
- CD58
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CD58 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- Antigen affinity
- Immunogen
- Amino acids F29-R215 from the human protein were used as the immunogen for the CD58 antibody.
- Isotyp
- IgG
- Top Product
- Discover our top product CD58 Primärantikörper
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- Applikationshinweise
- Optimal dilution of the CD58 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (FFPE): 0.5-1 μg/mL, FACS: 1-3 μg/10^6 cells
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Lagerung
- -20 °C
- Informationen zur Lagerung
- After reconstitution, the CD58 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Target
- CD58
- Andere Bezeichnung
- CD58 / LFA3 (CD58 Produkte)
- Synonyme
- LFA-3 antikoerper, LFA3 antikoerper, ag3 antikoerper, CD58 molecule antikoerper, CD58 antikoerper
- Hintergrund
- CD58, or lymphocyte function-associated antigen 3 (LFA-3), is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. It binds to CD2 (LFA-2) on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. This adhesion occurs as part of the transitory initial encounters between T cells and Antigen Presenting Cells before T cell activation, when T cells are roaming the lymph nodes looking at the surface of APCs for peptide:MHC complexes the T-cell receptors are reactive to. The LFA3 gene is mapped to chromosome 1p13, which is the same location as CD2.
- UniProt
- P19256
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