AFG3L2 Antikörper

Produktnummer ABIN4950041

Produktdetails anti-AFG3L2 Antikörper

Target: AFG3L2 (AFG3-Like Protein 2 (AFG3L2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AFG3L2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: Amino acids R168-D250 of the human protein were used as the immunogen for the AFG3L2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the AFG3L2 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the AFG3L2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu AFG3L2

Target: AFG3L2 (AFG3-Like Protein 2 (AFG3L2))

Andere Bezeichnung: AFG3L2 (AFG3L2 Produkte)

Synonyme: MGC147390 antikoerper, si:ch211-12e1.4 antikoerper, SCA28 antikoerper, SPAX5 antikoerper, 2310036I02Rik antikoerper, AW260507 antikoerper, Emv66 antikoerper, par antikoerper, AFG3 like matrix AAA peptidase subunit 2 antikoerper, AFG3-like protein 2 antikoerper, AFG3 ATPase family gene 3-like 2 (S. cerevisiae) antikoerper, AFG3-like AAA ATPase 2 antikoerper, AFG3-like AAA ATPase 2 L homeolog antikoerper, AFG3L2 antikoerper, LOC578526 antikoerper, afg3l2 antikoerper, afg3l2.L antikoerper, Afg3l2 antikoerper

Hintergrund: AFG3L2 is the catalytic subunit of the m-AAA protease, an ATP-dependent proteolytic complex of the mitochondrial inner membrane that degrades misfolded proteins and regulates ribosome assembly. In humans, it is encoded by the AFG3L2 gene. This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. And this gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders as well as spastic ataxia-neuropathy syndrome.

UniProt: Q9Y4W6

Pathways: Skeletal Muscle Fiber Development