CLTA/CLTB Antikörper (N-Term)

Produktnummer ABIN4949569

Produktdetails anti-CLTA/CLTB Antikörper

Target: CLTA/CLTB (Clathrin, Light Chain A/B (CLTA/CLTB))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CLTA/CLTB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (IF)

Aufreinigung: Protein G affinity chromatography

Immunogen: A recombinant N-terminal protein fragment from human Clathrin light chain was used as the immunogen for the Clathrin Light Chain antibody.

Klon: SPM174

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Clathrin Light Chain antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 1-2 μg/mL,WB: 0.5-1 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 min at RT

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the Clathrin Light Chain antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu CLTA/CLTB

Target: CLTA/CLTB (Clathrin, Light Chain A/B (CLTA/CLTB))

Andere Bezeichnung: Clatherin Light Chain (LCA/LCB) (CLTA/CLTB Produkte)

Synonyme: lca antikoerper, zgc:73358 antikoerper, wu:fb61d08 antikoerper, wu:fj48d06 antikoerper, LCA antikoerper, clc antikoerper, DDBDRAFT_0169251 antikoerper, DDBDRAFT_0191305 antikoerper, DDB_0169251 antikoerper, DDB_0191305 antikoerper, clcb antikoerper, clathrin light chain A antikoerper, clathrin, light chain A antikoerper, Clathrin light chain antikoerper, clathrin light chain antikoerper, clathrin light chain B antikoerper, Clathrin light chain B antikoerper, CLTA antikoerper, clta antikoerper, clic-1 antikoerper, CLC1 antikoerper, clc antikoerper, CLTB antikoerper, clcb antikoerper, CNI00580 antikoerper, LOC5567495 antikoerper, CpipJ_CPIJ018056 antikoerper, PTRG_01988 antikoerper, PMAA_096950 antikoerper, SJAG_04517 antikoerper, TSTA_044110 antikoerper, PAS_chr1-4_0158 antikoerper

Hintergrund: Recognizes proteins of 31-44  kDa, which are identified as Clathrin Light Chains (both A & B). Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin light chain regulates the self-assembly of triskelions onto intracellular membranes. Clathrin light chain subunits (LCA and LCB) contribute to regulation of coated vesicle formation to sort proteins during receptor-mediated endocytosis and organelle biogenesis. LCA and LCB are encoded by two discrete genes. They share only 60 % homology, and have certain features in common. Both LCA and LCB undergo alternative mRNA splicing, which results in the generation of tissue-specific isoforms.