PHKA2 Antikörper

Produktnummer ABIN4904749

Produktdetails anti-PHKA2 Antikörper

Target: PHKA2 (Phosphorylase Kinase, alpha 2 (PHKA2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHKA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, which are encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9A, also known as X-linked liver glycogenosis. Alternatively spliced transcript variants have been reported, but the full-length nature of these variants has not been determined.[provided by RefSeq, Feb 2010]

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human PHKA2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:200-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C.

Details zu PHKA2

Target: PHKA2 (Phosphorylase Kinase, alpha 2 (PHKA2))

Andere Bezeichnung: PHKA2 (PHKA2 Produkte)

Synonyme: GSD9A antikoerper, PHK antikoerper, PYK antikoerper, PYKL antikoerper, XLG antikoerper, XLG2 antikoerper, PHKA2 antikoerper, 6330505C01Rik antikoerper, D330034O08 antikoerper, Phk antikoerper, phosphorylase kinase regulatory subunit alpha 2 antikoerper, phosphorylase kinase alpha 2 antikoerper, PHKA2 antikoerper, Phka2 antikoerper

Gen-ID: 5256

UniProt: P46019

Pathways: Cellular Glucan Metabolic Process