ABCC8 Antikörper (AA 1559-1571)

Produktnummer ABIN490470

Produktdetails anti-ABCC8 Antikörper

Target: ABCC8 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8))

Bindungsspezifität: AA 1559-1571

Reaktivität: Human, Hund, Rind (Kuh), Pferd

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser ABCC8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: Human ABCC8 / MRP8.

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Elephant, Panda, Bovine, Dog, Horse (100%) Marmoset, Mouse, Rat, Bat, Rabbit, Pig (92%) Hamster (85%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide C-EFDKPEKLLSRKD from the C-terminus of human ABCC8 / MRP8 (NP_000343.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Elephant, Panda, Bovine, Dog, Horse (100%), Marmoset, Mouse, Rat, Bat, Rabbit, Pig (92%), Hamster (85%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: Peptide-ELISA (1:8000), WB (0.5 - 1.5 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:8000. Western blot: Approx 170  kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 177  kDa according to NP_000343.2). Recommended concentration: 0.5-1.5 μg/mL. An additional band of unknown identity was also consistently observed at 23  kDa. This band was successfully blocked by incubation with the immunising peptide.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu ABCC8

Target: ABCC8 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8))

Andere Bezeichnung: ABCC8 / SUR1 (ABCC8 Produkte)

Synonyme: ABC36 antikoerper, HHF1 antikoerper, HI antikoerper, HRINS antikoerper, MRP8 antikoerper, PHHI antikoerper, SUR antikoerper, SUR1 antikoerper, SUR1delta2 antikoerper, TNDM2 antikoerper, D930031B21Rik antikoerper, Sur antikoerper, Sur1 antikoerper, ATP binding cassette subfamily C member 8 antikoerper, ATP-binding cassette, sub-family C (CFTR/MRP), member 8 antikoerper, ABCC8 antikoerper, Abcc8 antikoerper

Hintergrund: Name/Gene ID: ABCC8
Subfamily: ATP-binding cassette - ABCC/MRP
Family: Transporter

Synonyms: ABCC8, ABC36, HI, PHHI, Sulfonylurea receptor, SUR, Sulfonylurea receptor 1, MRP8, SUR1delta2, HHF1, HRINS, SUR1, TNDM2

Gen-ID: 6833

NCBI Accession: NP_000343

UniProt: Q09428

Pathways: Negative Regulation of Hormone Secretion