MAPK8IP1 Antikörper

Produktnummer ABIN4904305

Produktdetails anti-MAPK8IP1 Antikörper

Target: MAPK8IP1 (Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPK8IP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: This gene encodes a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes.

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human MAPK8IP1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:200-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C.

Details zu MAPK8IP1

Target: MAPK8IP1 (Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1))

Andere Bezeichnung: MAPK8IP1 (MAPK8IP1 Produkte)

Synonyme: IB1 antikoerper, JIP-1 antikoerper, Jip1 antikoerper, Prkm8ip antikoerper, Skip antikoerper, mjip-2a antikoerper, JIP1 antikoerper, Jip-1 antikoerper, Mapk8ip antikoerper, PRKM8IP antikoerper, mitogen-activated protein kinase 8 interacting protein 1 antikoerper, MAPK8IP1 antikoerper, Mapk8ip1 antikoerper

Gen-ID: 9479

UniProt: Q9UQF2