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EEA1 Antikörper

EEA1 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN4903538
  • Target Alle EEA1 Antikörper anzeigen
    EEA1 (Early Endosome Antigen 1 (EEA1))
    Reaktivität
    • 77
    • 35
    • 30
    • 16
    • 9
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 53
    • 19
    • 3
    • 2
    • 1
    Kaninchen
    Klonalität
    • 59
    • 19
    Polyklonal
    Konjugat
    • 46
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EEA1 Antikörper ist unkonjugiert
    Applikation
    • 42
    • 19
    • 14
    • 13
    • 13
    • 12
    • 10
    • 8
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Produktmerkmale
    EEA1 is an early endosomal marker and a Rab5 effector protein essential for early endosomal membrane fusion and trafficking (1-2). The carboxy terminus of EEA1 contains a FYVE domain which binds to phosphatidylinositol-3-phosphate (PtdIns(3)P), targeting EEA1 to early endosomes (3). The stable association of EEA1 with the endosomal membrane is regulated by PI3 kinase, Rab5 and calcium/calmodulin (4-6). Once on the membrane, EEA1 interacts with Rab5, NSF and syntaxin 13 to promote early endosomal membrane docking and fusion (7).1.Mu, F.T. et al. (1995) J. Biol. Chem. 270, 13503-13511.2.Christoforidis, S. et al. (1999) Nature 397, 621-625.3.Gaullier, J.M. et al. (1998) Nature 394, 432-433.4.Patki, V. et al. (1997) Proc. Natl. Acad. Sci. USA 94, 7326-7330.5.Lawe, D.C. et al. (2003) Mol. Biol. Cell 14, 2935-2945.6.Simonsen, A. et al. (1998) Nature 394, 494-498.7.McBride, H.M. et al. (1999) Cell 98, 377-386.
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant Protein of human EEA1.
    Isotyp
    IgG
    Top Product
    Discover our top product EEA1 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C.
  • Target
    EEA1 (Early Endosome Antigen 1 (EEA1))
    Andere Bezeichnung
    EEA1 (EEA1 Produkte)
    Synonyme
    MST105 antikoerper, MSTP105 antikoerper, ZFYVE2 antikoerper, im:7151048 antikoerper, si:ch211-276p10.2 antikoerper, A430109M19Rik antikoerper, B230358H09Rik antikoerper, early endosome antigen 1 antikoerper, early endosome antigen 1 S homeolog antikoerper, EEA1 antikoerper, eea1 antikoerper, Eea1 antikoerper, eea1.S antikoerper
    Gen-ID
    8411
    UniProt
    Q15075
    Pathways
    Toll-Like Receptors Cascades
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