AUH Antikörper

Produktnummer ABIN4902991

Produktdetails anti-AUH Antikörper

Target: AUH (AU RNA Binding Protein/enoyl-CoA Hydratase (AUH))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AUH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktmerkmale: The methylglutaconyl-CoA hydratase, mitochondrial protein binds to the AU-rich element (ARE), a common element found in the 3' UTR of rapidly decaying mRNA such as c-fos, c-myc and granulocyte/ macrophage colony stimulating factor. ARE elements are involved in directing RNA to rapid degradation and deadenylation. AUH is also homologous to enol-CoA hydratase, an enzyme involved in fatty acid degradation, and has been shown to have intrinsic hydratase enzymatic activity. AUH is thus a bifunctional chimera between RNA binding and metabolic enzyme activity. A possible subcellular localization in the mitochondria has been demonstrated for the mouse homolog of this protein which shares 92 % identity with the human protein. It has been suggested that AUH may have a novel role as a mitochondrial located AU-binding protein. Human AUH is expressed as a single mRNA species of 1.8 kb, and translated as a 40- kDa precursor protein which is subsequently processed to a 32- kDa mature form.

Aufreinigung: Affinity purification

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C.

Details zu AUH

Target: AUH (AU RNA Binding Protein/enoyl-CoA Hydratase (AUH))

Andere Bezeichnung: AUH (AUH Produkte)

Synonyme: C77140 antikoerper, W91705 antikoerper, wu:fb81b10 antikoerper, zgc:101057 antikoerper, AU RNA binding methylglutaconyl-CoA hydratase antikoerper, AU RNA binding protein/enoyl-coenzyme A hydratase antikoerper, AU RNA binding protein/enoyl-CoA hydratase antikoerper, AU RNA binding protein/enoyl-CoA hydratase S homeolog antikoerper, AUH antikoerper, Auh antikoerper, auh antikoerper, auh.S antikoerper

Gen-ID: 549

UniProt: Q13825