AANAT Antikörper

Produktnummer ABIN4902802

Produktdetails anti-AANAT Antikörper

Target: AANAT (Aralkylamine N-Acetyltransferase (AANAT))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AANAT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide of human AANAT

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:1000

Kommentare:

Highly expressed in pineal gland and at lower levels in the retina, Weak expression in several brain regions and in the pituitary gland

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20C. Avoid freeze / thaw cycles.

Details zu AANAT

Target: AANAT (Aralkylamine N-Acetyltransferase (AANAT))

Andere Bezeichnung: AANAT (AANAT Produkte)

Synonyme: DSPS antikoerper, SNAT antikoerper, AA-NAT antikoerper, Nat4 antikoerper, Nat-2 antikoerper, Snat antikoerper, aralkylamine N-acetyltransferase antikoerper, arylalkylamine N-acetyltransferase antikoerper, AANAT antikoerper, Aanat antikoerper

Hintergrund: The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 23.344 kDa

Gen-ID: 15

UniProt: Q16613

Pathways: Photoperiodism